TBFY In Conversation 23 – Anthropomania with Jay Ingram

Science broadcaster extraordinaire Jay Ingram is back! As always our chat covers many topics. Can people benefit from watching science unfold in real time? The importance of context when delivering and receiving science based info. The real reasons people decide on “scientific debates”. We also talk at length about humanities relationships with animals and Jay’s new podcast Anthropomania which explores these relationships and the consequences for us and the animals. Check out anthropomania.com for more info and take a listen wherever you get your podcasts.

Be a part of the show by sending us your questions, comments or thoughts on Twitter, Instagram (@TwoBradForYou), by email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou. We will read and listen to everything you send and play/read your messages on the show.

TBFY In Conversation 22 – The Weight of Air with David Poses

My guest author David Poses has an incredibly important message, our entire system of drug prevention, policy and treatment needs to be blown up and rebuilt. David brings us this message in his upcoming book The Weight of Air which details his double life struggling with mental illness and heroin addiction. Through his experience and story the failures of the current shame based ways we deal with addiction and mental illness become clear as does the possibility for an alternative compassionate strategy. His book is available July 6th and open for pre-order now wherever books are sole. Check out davidposes.com for full details and follow David on Twitter, Instagram or Facebook.

Be a part of the show by sending us your questions, comments or thoughts on Twitter, Instagram (@TwoBradForYou), by email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou. We will read and listen to everything you send and play/read your messages on the show.

Episode 67-Freaky Research and Questions from the Mail Feed

Episode 66 was kind of all over the map. I touched on several bits of weird research that all have ethical concerns and answered a listener question about psychedelic therapy.

First up was the discussion on brain organoids that mimic infant brain development. The story cited was from FierceBiotech.com and can be found here. Other science outlets covered this one too so a quick search will turn up more on this. For an introduction to organoids the Wikipedia page is a good place to start.

The questions concerning psychedelic therapy brought up stuff that was discussed in my talk with VICE senior staff writer Shayla Love on TBFY In Conversation 20. You can check out her work here. It also touched on some things I covered in my podcast for Undark Magazine which you can find here. The placebo effect came up, along with the mention of convincing people they took a drug when in fact it was a placebo. This study is an example of that. A lot of my answer comes from the reporting I did for that podcast and reading of primary sources on psychedelics. If you’re interested again start with the Wikipedia, Shayla’s work and the Undark pod to get an overview. Reach out to me if you have further questions or try MAPS and The MIND Foundation. Both have links to resources and are at the forefront of the clinical trials. Finally, I also mentioned a Wiki page outlining the legality of psilocybin by country.

Rounding out the weird and freaky research topics was the story on human/monkey chimeras, in other words hybrid embryos. I mentioned both the Live Science story on the topic and The Economists article as well. The latter is behind a paywall but if you sign up you get 3 free articles a month. Both are worth a read and touch on the science and the ethical stuff. And finally, we have the re-infection trials upcoming at Oxford. This is the most interesting one for me and there isn’t any data to report yet. Just the info on what the trial will look like and what they are hoping to find, all of which can be found in Medical News Today.

Thanks as always for listening/reading and I want to mention that we set up a donations page for the show via Buy Me A Coffee. It is super easy to donate there and we appreciate any and all support. Mostly the costs are web hosting and online video call/interviewing subscriptions, plus my time researching, recoding, editing and posting. If you want to/can chip in that’d be great.

As always tell a friend about the show and get in touch so you too can be part of the show.

Be a part of the show by sending us your questions, comments or thoughts on Twitter, Instagram (@TwoBradForYou), by email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou. We will read and listen to everything you send and play/read your messages on the show.

Two Brad For You-Episode 67-Freaky Research and Questions from the Mail Feed

Brad, aka Flash, is here to answer questions from the mail feed and bring you some weird science regarding tiny lab grown brains, tiny human/monkey chimeras and folks that are volunteering to be re-infected with SARS 2.

The podcast is also launching a donations page via the Buy Me a Coffee service. It’s real easy to contribute if you feel like the show is worthwhile. Our main costs are web hosting and online video call/interviewing subscriptions plus the time it takes to produce the show. Every little bit helps.

Be a part of the show by sending us your questions, comments or thoughts on Twitter, Instagram (@TwoBradForYou), by email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou. We will read and listen to everything you send and play/read your messages on the show.

TBFY In Conversation 21 – Sharing Genomes and More with Stephen Doyle

Stephen Doyle is a molecular and computational biologist who uses whole genome sequencing to study how parasites evolve resistance to drugs. He was also able to explain how genome sequencing works and just how powerful that technology and data can be, especially in the context of the ongoing coronavirus situation. You’ve heard of corona variants, well Stephen helps sort out what this means and how genomics is used to track these outbreaks. We also discussed the benefits of pre-print for the field of genomics and the importance of open science. Check out his twitter @stephen__doyle and his work at the Sanger Institute.

Be a part of the show by sending us your questions, comments or thoughts on Twitter, Instagram (@TwoBradForYou), by email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou. We will read and listen to everything you send and play/read your messages on the show.

TBFY In Conversation 20 – Covering the Psychedelic Beat with Shayla Love

Senior staff writer at VICE Shayla Love was kind enough to join the show to discuss her work covering the psychedelics beat. Shayla writes feature articles on many topics that fall under the umbrellas of science, psychology, health and the mind and she is consistently finding unique and important angles of the psychedelic movement that need to be talked about, including the commodification and commercialization of psychedelic assisted therapy. She is an excellent writer and is full of great insights into this field and others. Please do give her a follow on Twitter, @shayla__love and check out all of her writing at VICE.

Be a part of the show by sending us your questions, comments or thoughts on Twitter, Instagram (@TwoBradForYou), by email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou. We will read and listen to everything you send and play/read your messages on the show.

Two Brad For Politics 7 – Tents, Size Does Matter

The panel of regular citizens is back to talk only Canadian politics this episode. They touch on the Supreme Court of Canada decision regarding carbon pricing, the fight everyone strategy of the Alberta Conservatives and the fight brewing within the federal Conservative party. Are they pitching too big a tent and where did those barnacles come from???

Be a part of the show by sending us your questions, comments or thoughts on Twitter, Instagram (@TwoBradForYou), by email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou. We will read and listen to everything you send and play/read your messages on the show.

Episode 66 – Leaky Labs, Lockdowns and Revived Ebola

I’ve been having a lot of conversations about both the lab leak and are lockdowns harmful questions recently and also found some interesting new takes on both, meaning we had enough for a pod. Plus there was some fascinating new Ebola news that needed to be shared. Here are the references and some thoughts on this episode.

Both the lab leak and lockdown issues are waaaayyy to politicized. Hot take I know. Thankfully, I’ve felt the temperature decrease since the shitstorm in chief left office and it appears as though the discussion may be able to take place more rationally. Wishful thinking? Maybe. When looking at both questions though it becomes clear to me that no one can say definitely if lab leak or natural spillover is more likely or acccurately quantify the harm from lockdowns. That’s right, this episode is some classic fence sitting. As it should be with these contentious issues.

When it comes to lab leak there are two recent pieces I found helpful. One is from Undark magazine, by Charles Schmidt titled Lab Leak: A Scientific Debate Mired in Politics — and Unresolved. The other which Charles links to and references in his piece is an opinion pieces by Dr. David Relman (a legit doctor and disease researcher) published in the academic journal PNAS. His piece, Opinion: To stop the next pandemic, we need to unravel the origins of COVID-19, does a really nice job laying out what we know, what we don’t and how that missing information is essential to determining the origin. Without it, no one can say for certain how SARS 2 entered the population. Until then we wait and question anyone who says they know for sure.

On the lockdown issue, I came across epidemiologist, writer (he has written for such publications as The Guardian and The Observer) and podcaster Gideon Meyerowitz-Katz. Give him a follow on Twitter at @GidMK. He also writes a blog on Medium and he has looked into some of the available regarding the harms of lockdowns. Two blogs you should definitely check out are What Are the Negative Effects of COVID-19 Lockdowns? and Have Lockdowns Caused Suicides During COVID-19?. The short answer to the question of harm caused by lockdowns is that, at least in the short term, there doesn’t appear to be an increase in suicide or death. Gideon covers this quite nicely and uses data from this preprint paper The World Mortality Dataset: Tracking excess mortality across countries during the COVID-19 pandemic to demonstrate that “lockdowns” such as the drastically restrictive one in Australia didn’t lead to excess mortality. Remember the caveats of preprint papers of course that we discussed with Martin Nielsen in the last TBFY In Conversation episode. Gideon also explains how it is incredibly difficult to tease out the cause of any increase in mental health issues or disruptions to health care. Are they from being locked down or a consequence of the raging pandemic itself. Point being, again, we can’t say they are harmful or harmless.

Finally, the Ebola update!! There is unfortunately a new outbreak as of February 14th in Guinea. If you remember Guinea was the source of the huge West Africa outbreak in 2014-2016. This current one is so far small and efforts are underway to vaccinate people in the area. The interesting and alarming new piece of data is that it appears as though this outbreak was started by an yet unidentified individual who was still carrying virus from the 2014-2016 outbreak. We have discussed post Ebola syndrome several times on the show, most recently in Episode 65. Post Ebola syndrome is when survivors of the disease are found with virus hiding out in the body, particularly in tissues that the immune system has trouble reaching, the eyes, the testicles and central nervous system. Now, it looks as though this virus can in some cases revive itself and be infectious once more. This obviously has huge implications for Ebola prevention and management and is a new attribute of the virus. We will follow this of course and keep you Ebola updated. For an overview of this new finding check out this NY Times piece or coverage from The Scientist.

Be a part of the show by sending us your questions, comments or thoughts on Twitter, Instagram (@TwoBradForYou), by email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou. We will read and listen to everything you send and play/read your messages on the show.

Two Brad For You – Episode 66 – Leaky Labs, Lockdowns and Revived Ebola

Brad, aka Flash, is here with some Friday afternoon thoughts on two overly politicized corona issues, the lab leak scenario and the harm from lockdowns. Spoiler alert, there is no definitive answer so get ready to sit on some fence. Stick around for some intriguing Ebola news at the end as well.

Be a part of the show by sending us your questions, comments or thoughts on Twitter, Instagram (@TwoBradForYou), by email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou. We will read and listen to everything you send and play/read your messages on the show.

TBFY In Conversation 19 – Communicating from The Ivory Tower with Martin Nielsen

It was a pleasure to host veterinary parasitologist and friend of the show Martin Nielsen for a discussion on science communication from an academic perspective. Lessons learned, challenges, issues with pre-print publishing, restoring faith in expertise and much more. Follow Martin on Twitter, @MartinKNielsen and Youtube, Martin K Nielsen Equine Parasitology.

As always please rate and subscribe wherever you get podcasts and get in touch on Twitter or Instagram. You can also send us an email at twobradforyou@gmail.com or leave a voice message at www.speakpipe.com/twobradforyou, we will read and play what you send us on the show.

For full show notes and links to our sources head-over to: https://twobradforyou.wordpress.com/category/tbfy-blog/